What is Neuroleptic Malignant Syndrome (NMS)?

Neuroleptic Malignant Syndrome (NMS) is a rare but serious reaction to antipsychotic medications, characterized by severe muscle rigidity, elevated temperatures, autonomic instability, and altered mental status. The condition can occur after starting a new antipsychotic medication or increasing the dose of an existing one. Due to its potential to progress rapidly and lead to life-threatening complications, NMS requires immediate medical attention.

Understanding the nature of NMS emphasizes the importance of monitoring patients closely when they are prescribed antipsychotics. Early identification and intervention can be crucial in managing this syndrome, which may involve immediate discontinuation of the antipsychotic medication, supportive care, and sometimes specific pharmacological treatments. The recognition that NMS is a serious condition underscores the need for healthcare professionals to be vigilant about the signs and symptoms in patients who are on these medications.